Effie Gray

Dakota Fanning

Euphemia 'Effie' Gray

Emma Thompson

Lady Eastlake

Greg Wise

John Ruskin

Tom Sturridge

Everett Millais

Robbie Coltrane

Doctor

Julie Walters

Margaret Cox Ruskin

Derek Jacobi

Travers Twiss

Claude Cardinale

Viscountess

David Suchet

Mr. Ruskin

James Fox

Sir Charles Eastlake

Patrick Doyle

Wedding Minister

Russell Tovey

George

Linda Bassett

Anna

Pip Torrens

Royal Academy / Times Journalist

Nicholas Jones

Doctor Lee

Joanna Hole

Mrs. McPhail (uncredited)

Riccardo Scamarcio

Rafael

Polly Dartford

Sophie Gray

Tom Herriott

William Holman Hunt

Sam Churchill

Dante Gabriel Rossetti